Condition
Peripheral Neuropathy
A Numbing Sensation
Overview
100
Different types of peripheral neuropathy identified by scientists to date
50
The age at which people are at higher risk for most peripheral neuropathies
2.4%
People affected by peripheral neuropathy — increases more than three times in older populations
In plain language
Peripheral neuropathy is a condition that affects the nerves outside the brain and spinal cord, often leading to numbness, tingling, and weakness in the hands and feet. It can result from various underlying health conditions, including diabetes, vitamin deficiencies, and autoimmune disorders. As we age, the risk of developing peripheral neuropathy increases.
Peripheral neuropathy is a condition that affects the nerves outside the brain and spinal cord. When these nerves become damaged, they may not transmit signals properly, leading to various symptoms.
The exact cause of peripheral neuropathy can vary, but it often arises from underlying health conditions such as diabetes, vitamin deficiencies, or autoimmune disorders.
Understanding the underlying causes of peripheral neuropathy is crucial for effective management. By addressing the underlying condition and managing symptoms, individuals can improve their quality of life and reduce the risk of complications.
Common types of peripheral neuropathy include:
- Diabetic neuropathy: Caused by damage to nerves due to high blood sugar levels.
- Alcoholic neuropathy: Resulting from nerve damage caused by excessive alcohol consumption.
- Vitamin deficiency neuropathy: Caused by deficiencies in vitamins such as B1, B6, and B12.
- Autoimmune neuropathy: Arises from autoimmune disorders that attack the nerves.
- Idiopathic neuropathy: Occurs without a known cause.
Key Information
Review the most relevant symptoms, risk factors, and common care approaches in one place.
Risk Factors
Several factors can contribute to the development of peripheral neuropathy, including:
Diabetes: High blood sugar levels can damage nerves over time.
Alcohol abuse: Excessive alcohol consumption can damage nerves.
Vitamin deficiencies: Deficiencies in vitamins B1, B6, and B12 can lead to nerve damage.
Autoimmune disorders: Conditions such as rheumatoid arthritis and lupus can attack nerves.
Infections: Certain infections, such as shingles, can damage nerves.
Medications: Some medications, such as chemotherapy drugs, can have nerve damage as a side effect.
Symptoms
The symptoms of peripheral neuropathy can vary depending on the nerves affected. Common symptoms include:
Numbness: A loss of sensation in the hands, feet, or other areas of the body.
Tingling: A prickling or tingling sensation in the affected areas.
Pain: Sharp, burning, or shooting pain.
Weakness: Muscle weakness, particularly in the hands and feet.
Loss of coordination: Difficulty with balance and coordination.
Coping Strategies
Treatments That May Help
Start with the options that have more supporting research and then review the details with your care team.
Treatment Option
Acetyl-L-Carnitine
Acetyl-L-carnitine (ALCAR) is an amino-acid-derived nutrient that helps the body convert fat into energy. It supports healthy nerve function and may enhance memory and alertness in older adults experiencing fatigue or mild cognitive changes.
7 studies
Read more →
Treatment Option
Alpha-lipoic Acid
Alpha-lipoic acid (ALA) is a natural antioxidant that supports nerve function, glucose metabolism, and healthy aging. It helps protect cells from oxidative stress, which contributes to nerve pain and fatigue.
4 studies
Read more →
Take the next step
Discover evidence-based treatments and research for peripheral neuropathy.