Ashwagandha May Cause Neuropsychiatric Issues in Some Adults

This article is based on a detailed medical case report describing a possible rare side effect linked to ashwagandha.

• Study design (in simple terms): A single-person case report. Doctors documented symptoms, timing, testing, and recovery after stopping the supplement.

• Key findings (with numbers): Symptoms began a few hours after taking two tablets (total 500 mg). The patient slept about 23 hours and arrived confused with a 4AT delirium screening score of 10 (a high score). CT and MRI brain scans were normal. Spinal fluid testing for infections (including HSV and VZV) was negative. He improved within hours and returned to baseline by day 3. A causality tool (Naranjo scale) scored the reaction as 7 = “probable”.

• Limitations/caveats: This is only one case, so it cannot tell us how often this happens or who is most at risk. The supplement brand and purity can vary, and an EEG (a brain-wave test) was not done. Case reports can suggest a warning signal but do not prove cause for everyone.

• Practical implications for daily life: If you take ashwagandha, be cautious with dose increases, and watch for excessive sleepiness, vivid/strange dreams, confusion, unsteady walking, or unusual nighttime behaviors. Avoid mixing supplements with sedating medications or alcohol unless your clinician says it’s safe. If sudden confusion occurs, treat it as urgent and seek medical care.

Bring a full list of all supplements (including “natural” products) to your healthcare provider or pharmacist, especially if you take medicines for blood pressure, mood, sleep, or pain.