Study
This comprehensive 2025 review found that creatine supplementation enhances muscle performance in both novice and experienced lifters, including ad...
In plain language
This comprehensive 2025 review found that creatine supplementation enhances muscle performance in both novice and experienced lifters, including adults over 60. Benefits included improved muscle mass, strength, and overall function when combined with resistance exercise. The study confirmed a strong safety profile and recommended creatine as a viable support for age-related muscle loss prevention.
Use the full description to understand the study design, methods, and the limits of the findings.
This meta-analysis examined creatine supplementation combined with resistance training across age groups, including older adults. Results show significant improvements in muscle mass, strength, and function, particularly in untrained or sarcopenic individuals. No major adverse effects were reported with daily doses up to 5 grams.
Open the original publication for the complete methods, outcomes, and source material.
Published December 2025
Opens at the publisher · external site · may require institutional access
The study is a well-conducted systematic review and meta-analysis that provides valuable insights into the effects of creatine supplementation on muscle performance. It is methodologically sound but could improve in areas such as bias control and transparency. Overall, it contributes meaningfully to the existing literature.
| Category | Score | Rating |
|---|---|---|
| Study Design / Evidence Level | 8.3/10 | |
| Bias & Methods | 6.7/10 | |
| Statistical Integrity | 7.5/10 | |
| Transparency | 7.5/10 | |
| Conflict of Interest Disclosure | 10.0/10 | |
| Replication / External Validation | 5.0/10 | |
| Relevance to Seniors | 10.0/10 | |
| Journal Quality | 7.5/10 |
The study could benefit from more detailed reporting on the heterogeneity of included studies and potential publication bias. Future research should focus on long-term effects and different dosing strategies.
Build a personalized plan using research-backed studies, conditions, and treatments.