Study
Grape Seed Extract Reduces Vein Problems in Older Adults
Taking grape seed extract twice daily significantly improved vein health in seniors with varicose veins.
Summary
In plain language
A recent study found that taking grape seed extract can help reduce vein problems in seniors with varicose veins. Participants who took the extract twice a day for 12 weeks experienced a noticeable improvement in vein function and reported fewer symptoms like leg pain and swelling. This is important because varicose veins affect many older adults and can lead to discomfort and further complications if untreated. The study suggests that grape seed extract could be a helpful addition to lifestyle changes for managing varicose veins. Seniors should consider discussing this option with their healthcare providers to see if it's suitable for them.
Details
Use the full description to understand the study design, methods, and the limits of the findings.
This study was a randomized controlled trial involving adults aged 19 to 80 years with varicose veins. Participants were divided into two groups: one received grape seed extract, and the other followed lifestyle changes alone. The study measured vein health using ultrasound and symptom questionnaires.
Participants taking grape seed extract showed significant reductions in venous reflux time, a key measure of vein health.
Those in the extract group reported better symptom relief and quality of life scores than those who did not take the extract.
The study had a limited duration of 12 weeks, and further long-term research is needed to confirm these findings.
If you have varicose veins, discuss with your healthcare provider if grape seed extract could be beneficial for you.
Full Study
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Grape Seed Extract Reduces Vein Problems in Older Adults
Published October 2026
Opens at the publisher · external site · may require institutional access
Research Quality Score
Scored October 8, 2026 using rubric mq-1.8_2026-07-06.
Assessment
The study scored well in study design and statistical integrity due to its RCT nature and robust statistical methods. However, it lacked blinding, affecting bias control. Transparency was high with registration and protocol sharing. The conflicts score was reduced due to industry funding, and relevance was partial as the study included a wide age range without specific focus on seniors. Journal quality could not be assessed.
Category Breakdown
| Category | Score | Rating |
|---|---|---|
| Study design | 10.0/10 | |
| Bias control | 3.3/10 | |
| Statistical methods | 10.0/10 | |
| Reporting completeness | 10.0/10 | |
| Conflicts & funding | 7.5/10 | |
| Replication | 0.0/10 | |
| Relevance to chosen population | 5.0/10 | |
| Journal Reliability | 5.0/10 |
Additional Notes
The VICTORY trial, an open-label RCT, evaluated the effects of Vitis vinifera seed extract on venous reflux time in varicose vein patients. The extract significantly reduced reflux time and improved symptoms compared to lifestyle changes alone.
Assessed on the study's full text across 8 quality dimensions; conflict-of-interest disclosures were reviewed.
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