Study
Natural Supplement Offers Symptom Relief for Enlarged Prostate
A study found that a supplement from saw palmetto, selenium, and lycopene helps reduce urinary symptoms in older men, without affecting sexual function.
Prostate HealthSupplementsMen's Health
Summary
In plain language
A recent study explored how a natural supplement, combining Serenoa repens (saw palmetto), selenium, and lycopene, affects symptoms of an enlarged prostate in older men. The study showed this supplement can help reduce urinary symptoms similar to the drug Dutasteride, but without the side effects related to sexual function often seen with medications. Conducted over a year with men aged 55 to 80, the research highlighted that while both treatments improved urinary symptoms, the natural supplement did not diminish sexual health. This is encouraging news for seniors looking for effective prostate symptom management without compromising quality of life.
Details
Use the full description to understand the study design, methods, and the limits of the findings.
The study involved 269 men aged 55 to 80, comparing the effects of a natural supplement (Serenoa repens, selenium, and lycopene) to the medication Dutasteride for prostate symptoms.
The research found both treatments improved urinary symptoms, but the supplement did not affect sexual function, unlike Dutasteride.
While Dutasteride reduced prostate size more significantly, the supplement offered similar symptom relief without sexual side effects.
Participants should know that while effective, the supplement may not reduce prostate size as much as the medication.
Talk with your healthcare provider to see if this supplement might be a suitable option for managing prostate symptoms.
Full Study
Open the original publication for the complete methods, outcomes, and source material.
Peer-reviewed publication · RCT
Natural Supplement Offers Symptom Relief for Enlarged Prostate
Published January 2025 · DOI 10.3389/fruro.2025.1565240
Opens at the publisher · external site · may require institutional access
Research Quality Score
Assessment
The study is a prospective non-randomized case-control design, which limits its evidence level due to lack of randomization. Bias control is limited by the non-randomized design and shared decision-making for treatment assignment. Statistical methods are appropriate but lack comprehensive reporting of power and effect sizes. Transparency is partial, with methods described but no protocol registration. Conflict of interest disclosure is present, but potential industry ties are a concern. The study is highly relevant to seniors, focusing on older men with BPH. Published in a reputable journal, but not top-tier.
Category Breakdown
| Category | Score | Rating |
|---|---|---|
| Study Design / Evidence Level | 5.0/10 | |
| Bias & Methods | 3.3/10 | |
| Statistical Integrity | 5.0/10 | |
| Transparency | 5.0/10 | |
| Conflict of Interest Disclosure | 5.0/10 | |
| Replication / External Validation | 0.0/10 | |
| Relevance to Seniors | 10.0/10 | |
| Journal Quality | 5.0/10 |
Additional Notes
The study's non-randomized design and potential conflicts of interest are significant limitations. Further replication and validation are needed to strengthen findings.
Conditions This Research Covers
These condition pages help connect the paper back to the real-world health concerns it addresses.
Health Condition
Benign Prostatic Hyperplasia (BPH)
Benign prostatic hyperplasia (BPH) is a common condition that affects men as they age. It involves an enlargement of the prostate gland, which can lead to urinary symptoms such as frequent urination, difficulty urinating, and a weak urine stream.
7 studies
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Health Condition
Erectile Dysfunction
Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for sexual activity. It is common among older men and can be influenced by both physical and emotional factors.
4 studies
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Treatments Evaluated in This Research
Review the interventions studied here and compare them against the broader treatment library.
Treatment Option
Dietary Management
Dietary management focuses on making thoughtful food choices to maintain good health, prevent disease, and manage chronic conditions. For seniors, balanced nutrition supports energy, mobility, and overall well-being while helping manage blood pressure, cholesterol, and digestion.
8 studies
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Treatment Option
Saw Palmetto (Serenoa repens)
Saw Palmetto supports prostate health and urinary comfort by helping balance hormone activity.
4 studies
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Treatment Option
Selenium
Selenium supports thyroid hormone production, antioxidant defense, and immune function.
3 studies
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Treatment Option
Calcium citrate
Calcium citrate is a bioavailable form of calcium that supports bone density, muscle function, and cardiovascular health. It’s especially useful for older adults with lower stomach acid or those taking acid-reducing medications.
2 studies
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