Study
Over-the-Counter Supplements Offer Mixed Results for Tinnitus Relief in Adults
Some over-the-counter supplements may help reduce the impact of tinnitus, but evidence is inconsistent.
Hearing HealthSupplementsQuality of Life
Summary
In plain language
Researchers investigated whether over-the-counter (OTC) supplements like melatonin and Ginkgo biloba can alleviate tinnitus symptoms in adults. The study reviewed nine clinical trials, finding that some supplements showed potential in reducing the perceived handicap of tinnitus, while others did not. Notably, products like Neurotec and Cistanche Yishen granules demonstrated a decrease in symptom severity. However, the evidence is mixed due to small study sizes and variations in trial designs. This research is important for seniors experiencing tinnitus, as it highlights that while some OTC options may offer relief, results can vary. It's crucial to discuss these findings with healthcare providers to explore personalized treatment options.
Details
Use the full description to understand the study design, methods, and the limits of the findings.
This study reviewed nine clinical trials focusing on the effects of OTC supplements on tinnitus symptoms.
The study examined various supplements, including melatonin and Ginkgo biloba, using the Tinnitus Handicap Inventory to measure results.
While some supplements showed promise in reducing tinnitus-related challenges, the findings were inconsistent, with placebo effects also noted.
Small sample sizes and different study designs limited the strength of the conclusions.
Seniors should consider discussing these findings with healthcare providers to determine if OTC options might be suitable for their tinnitus management.
Full Study
Open the original publication for the complete methods, outcomes, and source material.
Peer-reviewed publication · Meta-Analysis
Over-the-Counter Supplements Offer Mixed Results for Tinnitus Relief in Adults
Published January 2026 · DOI 10.1002/lio2.70398
Opens at the publisher · external site · may require institutional access
Research Quality Score
Assessment
The study scored well in study design and transparency due to its systematic approach and adherence to PRISMA guidelines. However, the lack of a quantitative meta-analysis and unspecified journal quality limited its scores in statistical integrity and journal quality. The absence of conflicts of interest disclosure was a positive factor.
Category Breakdown
| Category | Score | Rating |
|---|---|---|
| Study Design / Evidence Level | 10.0/10 | |
| Bias & Methods | 6.7/10 | |
| Statistical Integrity | 5.0/10 | |
| Transparency | 10.0/10 | |
| Conflict of Interest Disclosure | 10.0/10 | |
| Replication / External Validation | 0.0/10 | |
| Relevance to Seniors | 5.0/10 | |
| Journal Quality | 0.0/10 |
Additional Notes
This meta-analysis evaluates the efficacy of over-the-counter supplements for tinnitus relief using the Tinnitus Handicap Inventory (THI) as the primary outcome. It includes nine RCTs but does not perform a quantitative synthesis due to heterogeneity.
Assessed on the study's full text across 8 quality dimensions; conflict-of-interest disclosures were reviewed.
Treatments Evaluated in This Research
Review the interventions studied here and compare them against the broader treatment library.
Treatment Option
Supplements
Supplements help fill nutritional gaps and support healthy aging. For seniors, vitamins, minerals, and omega-3s can enhance bone strength, heart health, energy, and immune function when used safely under professional guidance.
74 studies
Read more →
Treatment Option
Melatonin
Melatonin is a hormone that regulates the sleep–wake cycle. Supplemental melatonin supports better sleep quality and helps older adults maintain consistent rest patterns.
12 studies
Read more →
Treatment Option
Ginkgo Biloba
Ginkgo biloba is an ancient herbal extract used to improve memory, focus, and blood flow. It supports cognitive performance and circulation, particularly in older adults.
11 studies
Read more →
Take the next step
Build a personalized plan using research-backed studies, conditions, and treatments.