Skip to main content

Study

Whey Protein Boosts Vitamin B12 Levels in Older Adults

Daily whey protein intake over a year significantly increased vitamin B12 levels in adults aged 65 and older.

NutritionHealthy AgingSupplement
Study Credibility: Medium7.2/10Some supporting evidenceStudy has limitationsUse with caution
PublishedSep 2026Last reviewedSep 2026
Email this

Summary

In plain language

A recent study found that taking whey protein supplements daily for one year can increase vitamin B12 levels in healthy older adults. Researchers looked at 167 participants aged 65 and older who received either whey protein, collagen, or carbohydrate supplements. Those taking whey protein showed a notable rise in vitamin B12 and holotranscobalamin, which is vital for vitamin absorption and use in the body. This suggests whey protein could be an effective way to improve B12 status, which is crucial for maintaining energy and nerve health. Seniors might find this information useful when considering dietary changes to support their health.

Details

Use the full description to understand the study design, methods, and the limits of the findings.

This study involved 167 healthy older adults who were divided into groups receiving different supplements: whey protein, collagen, or carbohydrates. Participants were also divided into different exercise regimes, including heavy and light resistance training or no exercise. The study measured vitamin B12-related biomarkers at various intervals.

  • Participants taking whey protein showed significant increases in vitamin B12 and holotranscobalamin levels over one year.

  • Collagen and carbohydrate supplements did not show similar benefits for B12 levels, highlighting whey protein's unique advantages.

  • Blood samples were affected by whether participants were fasting or not, indicating potential variability in measurement.

Seniors considering whey protein for its potential benefits should discuss this with their healthcare providers, especially if concerned about vitamin B12 levels.

Research Quality Score

Scored September 28, 2026 using rubric mq-1.8_2026-07-06.

Assessment

The study scores well in study design due to its randomized controlled trial format. Bias control is moderate due to lack of blinding details. Statistical methods are standard but lack power analysis. Transparency is high with pre-registration and ethical compliance. Conflicts are partially disclosed, affecting the score. The study is relevant to the target population but lacks replication and journal quality information.

Category Breakdown

CategoryScoreRating
Study design10.0/10
Bias control6.7/10
Statistical methods7.5/10
Reporting completeness10.0/10
Conflicts & funding5.0/10
Replication0.0/10
Relevance to chosen population10.0/10
Journal Reliability5.0/10

Additional Notes

The study investigates the effects of whey protein supplementation on vitamin B12 biomarkers in older adults over a year. It finds that whey protein increases B12 and holotranscobalamin levels, with no significant effect from collagen or carbohydrate supplements.

Assessed on the study's full text across 8 quality dimensions; conflict-of-interest disclosures were reviewed.

Take the next step

Build a personalized plan using research-backed studies, conditions, and treatments.