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Treatment

Vitamin K2 (Menaquinone-7)

Supports bone strength and heart health

1 medium-credibility studyStudies2Conditions4CategoryCAMLast reviewedJan 2026
Complementary and Alternative Medicine (CAM)
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Overview

In plain language

Vitamin K2 (MK-7) is a fat-soluble vitamin that directs calcium to bones and teeth while keeping it out of arteries and soft tissues. It works synergistically with vitamin D3 for optimal bone and cardiovascular health.

Vitamin K2 activates proteins that direct calcium to bones and teeth rather than blood vessels. This dual action improves skeletal integrity and reduces arterial calcification. For seniors, K2 works synergistically with vitamin D3 and calcium to strengthen bones and protect heart health. Commonly found in fermented foods or supplements as menaquinone-7 (MK-7), it supports long-term mobility and circulatory resilience.

Benefits

Use this section to compare the kinds of benefits people most often look for from this treatment.

General Benefits

Vitamin K2 activates proteins that regulate calcium distribution throughout the body. It supports bone mineralization by activating osteocalcin, which helps incorporate calcium into bone tissue, while also activating matrix GLA protein (MGP) to prevent calcium from depositing in arteries.

Physical Benefits

  • Strengthens bones: Improves calcium absorption into bone tissue.

  • Protects arteries: Prevents calcium buildup in vessel walls.

  • Supports dental health: Promotes mineralization of teeth.

  • Enhances joint flexibility: Keeps connective tissues resilient.

  • Works with vitamin D3: Improves calcium metabolism and synergy.

Mental Benefits

Emerging research suggests vitamin K2 may support brain health through its role in sphingolipid metabolism, which is important for maintaining healthy brain cell membranes. Healthy cardiovascular function supported by K2 also ensures adequate blood flow to the brain.

Additional Information

Related Conditions: Osteoporosis, heart disease, atherosclerosis, tooth decay, muscle weakness, circulatory issues, joint stiffness

Conditions This May Help With

See where this treatment appears most often and review the related condition pages for context.

Health Condition

Heart Disease

Heart disease, also known as cardiovascular disease, is a broad term that encompasses a range of conditions affecting the heart and blood vessels. It is a leading cause of death worldwide, particularly among older adults.

9 studies
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Health Condition

Stiffness

Stiffness, often characterized by a limited range of motion in joints, is a common complaint, particularly among older adults. It can affect various joints, including the knees, hips, shoulders, and back. While it can be a normal part of aging, stiffness can also be a symptom of underlying health conditions.

3 studies
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Health Condition

Osteoporosis

Osteoporosis, often referred to as the "silent disease," is a condition characterized by a decrease in bone mineral density, leading to weakened bones and an increased risk of fractures. As bones become more fragile, even minor falls or bumps can cause serious injuries. While osteoporosis can affect people of all ages, it is particularly common among postmenopausal women and older adults.

1 study
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Health Condition

Peripheral Artery Disease (PAD)

Peripheral artery disease (PAD) is a circulatory condition that affects the blood flow to the limbs, primarily the legs. It occurs when the arteries that supply blood to the legs become narrowed or blocked, typically due to a buildup of plaque within the artery walls. This plaque, composed of cholesterol, fat, and other substances, restricts blood flow, depriving the legs of essential oxygen and nutrients.

1 study
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Frequently Asked Questions About Vitamin K2 (Menaquinone-7)

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